2 edition of Biological microarrays found in the catalog.
Includes bibliographical references and index.
|Statement||edited by Ali Khademhosseini, Kahp-Yang Suh, Mohammed Zourob|
|Series||Springer protocols, Methods in molecular biology -- 671, Springer protocols, Methods in molecular biology -- v. 671.|
|LC Classifications||QP624.5.D726 B56 2011|
|The Physical Object|
|Pagination||xi, 324 p. :|
|Number of Pages||324|
|ISBN 10||1934115959, 1597455512|
|ISBN 10||9781934115954, 9781597455510|
|LC Control Number||2010938723|
This book provides a comprehensive guide to the use of DNA microarrays in neuroscience and provides approaches that are applicable to other complex biological systems. Human nervous system tissue is remarkably complex. Why Microarrays? Simultaneous analysis of thousands of genes Discovery of gene functions Biological replicates: utilize independently collected biosamples Books & Documentation simpleR - Using R for Introductory Statistics(Gentleman et al., ).
Dr. Rogers is an author on more than 60 scientific publications and book chapters, presented at national scientific meetings, actively serves on multiple scientific journal Editorial Boards, and served as Book Editor of Microarrays: Principles, Applications and Technologies (Nova Science Publishers, ). Electronic books: Additional Physical Format: Print version: DNA microarrays for biomedical research. New York: Humana, © (DLC) (OCoLC) Material Type: Document, Internet resource: Document Type: Internet Resource, Computer File: All Authors / Contributors: Martin Dufva.
While strong biological inferences can be made from microarray transcriptional data, they must be made within the proper biological and experimental context. This is because DNA microarrays capture a static view of a dynamic molecular event. This static view challenges researchers to tease out meaningful biological changes from the associated. Data Analysis Tools for DNA Microarrays book. Data Analysis Tools for DNA Microarrays. DOI link for Data Analysis Tools for DNA Microarrays. Data Analysis Tools for DNA Microarrays book. By Sorin Draghici. Technology today allows the collection of biological information at an unprecedented level of detail and in increasingly vast quantities.
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In Biological Microarrays: Methods and Protocols, expert researchers explore exciting new developments in the field, providing a comprehensive approach to biological microarrays that conveys not only the state-of-the-art fundamentals, but also includes applications of the most innovative : Humana Press.
In Biological Microarrays: Methods and Protocols, expert researchers explore exciting new developments in the field, providing a comprehensive approach to biological microarrays that conveys not only the state-of-the-art fundamentals, but also includes applications of the most innovative methods.
Chapters address both the application of. In Biological Microarrays: Methods and Protocols, expert researchers explore exciting new developments in the field, providing a comprehensive approach to biological microarrays that conveys not only the state-of-the-art fundamentals, but also includes applications of the most innovative methods.
ISBN: OCLC Number: Description: xi, pages: illustrations ; 27 Biological microarrays book. Contents: RNA and DNA microarrays / Stuart C.
Sealfona nd Tearina T. Chu --Aptamer arrays / Eva Baldrich --Oligonucleotide microarrays for identification of microbial pathogens and detection of their virulence-associated or drug. Further progress in microarrays is being spurred by the advances in micro- and nano-fabrication technologies, modern molecular biology, and data mining.
This book is designed to be a useful source of fundamental and current information for microarray research practitioners and for those who are just entering this field. Biological and Medical Physics Series, ISSN Biological and Medical Physics, Biomedical Engineering, ISSN Microarray Technology and Its Applications, Dan V.
Nicolau: Author: Uwe R. Müller: Editors: Uwe R. Müller, Uwe R. Müller, Dan V. Nicolau, Miguel Nicolau, Springer-Verlag (Berlin). Edition: illustrated: Publisher.
A DNA microarray (also commonly known as DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid ists use DNA microarrays to measure the expression levels of large numbers of genes simultaneously or to genotype multiple regions of a genome.
Each DNA spot contains picomoles (10 −12 moles) of a specific DNA sequence. For example, the differences between traditional biostatistical data sets and approaches to genetic epidemiology are compared and contrasted with the data sets resulting from microarrays.
Later in the book, the authors discuss the use of supervised and unsupervised learning techniques for various types of biological experiments, and the types. Biological Microarrays Methods and Protocols Edited by Ali Khademhosseini Department of Medicine, MIT Division of Health Sciences and Tech, Harvard Medical School, Cambridge, MA.
In this book I have tried to include topics that ranges from basic histology to the latest techniques of biological sciences like recombinant DNA technology, PCR mutagenesis, microarrays etc.
The book is very well organized and well written, and covers many of the major topics of microarrays experiments A nice feature of this book, and one which makes it very pleasant to read, is the use of full-color illustrations and plots, as well as boxes with some highlighted information, such as biological and statistical concepts.
DNA microarrays are solid supports, usually of glass or silicon, upon which DNA is attached in an organized pre-determined grid fashion.; Each spot of DNA, called a probe, represents a single gene. DNA microarrays can analyze the expression of tens of thousands of genes simultaneously.
Roderic Guigó, in Handbook of Systems Biology, DNA Microarrays. DNA microarrays (or DNA chips) have been the most commonly used technique during the last two decades to globally monitor cellular abundances of transcript species.
A DNA microarray is a collection of microscopic DNA spots attached to a solid surface. Each DNA spot contains many thousands of copies of. Part of the Methods in Molecular Biology book series (MIMB, volume Galloway A.L.
et al. () Micromolding for the Fabrication of Biological Microarrays. In: Khademhosseini A., Suh KY., Zourob M. (eds) Biological Microarrays. Methods in Molecular Biology (Methods and Protocols), vol Humana Press, Totowa, NJ.
The last section focuses on relating gene expression data with other biological In the case of microarrays, the spots are arranged in an orderly manner into sub-arrays or pen groups (Figure 1A), which makes spot identifi cation straightforward.
Most image Figure 2. Zooming onto a spot on the microarray slide. Microarrays: Preparation, Microfluidics, Detection Methods, and Biological Applications (Integrated Analytical Systems) - Kindle edition by Dill, Kilian, Liu, Robin, Grodzinsky, Piotr.
Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Microarrays: Preparation, Microfluidics, Manufacturer: Springer. What is the future outlook for microarrays in molecular biology research.
As the data analysis and the biological interpretation of gene expression data is regarded as the most time-consuming part of a typical microarray, the prospect of future DNA microarrays that would increase even further the amount of data retrieved per sample stresses the importance to continue investing.
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DNA Microarrays and Related Genomics Techniques: Design, Analysis, and Interpretation of Experiments consolidates discussions of methodological advances into a single volume.
The book’s structure parallels the steps an investigator or an analyst takes when conducting and analyzing a microarray experiment from conception to interpretation. Protein Microarrays is the first comprehensive treatment of protein microarray technology and includes detailed descriptions of manufacturing methods, surface chemistry, detection strategies, and data analysis for antigen, antibody, and peptide microarray assays.
The book also presents numerous biological applications and experimental protocols. Expression profiling using microarrays identifies genes whose expression depends on a specific biological state.
For example, the amount of gene mRNAs can be more abundant during a disease state biological condition than in a normal state. Genes expressed in the disease state can then be identified using microarrays.Book Description DNA microarrays are the modern, parallel version of classic molecular biology hybridization techniques allowing the exploration of thousands of sequences in a single run.
The technique permits the complete analysis of genetic material and the monitoring of expression changes occurring in a biological sample under various.Combinatorial chemistry is used to find materials that form sensor microarrays.
This book discusses the fundamentals, and then proceeds to the many applications of microarrays, from measuring gene expression (DNA microarrays) to protein-protein interactions, peptide chemistry, carbodhydrate chemistry, electrochemical detection, and : $